Our objetive
studying adipose tissue biology with special emphasis on the effects of lipolysis and other fat tissue adaptation mechanisms associated with negative energy balance and the onset of lactation on host immunity and disease susceptibility
Publications
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Transcriptome dataset of omental and subcutaneous adipose tissues from gestational diabetes patients.
Gestational diabetes (GD) is one of the most prevalent metabolic diseases in pregnant women worldwide. GD is a risk factor for adverse pregnancy outcomes, including macrosomia and preeclampsia. Given the multifactorial etiology and the complexity of its pathogenesis, GD requires advanced omics analyses to expand our understanding of the disease.
Developmental alterations of intestinal SGLT1 and GLUT2 induced by early weaning coincides with persistent low-grade metabolic inflammation in female pigs.
Early-life adversity (ELA) is linked with the increased risk for inflammatory and metabolic diseases in later life, but the mechanisms remain poorly understood. Intestinal epithelial glucose transporters sodium-glucose-linked transporter 1 (SGLT1) and glucose transporter 2 (GLUT2) are the major route for intestinal glucose uptake but have also received increased attention as modulators.
As hypertension develops, the forces exerted by blood pressure are applied to the vessels’ structures inducing pathological changes in the cellular components of the vasculature. These changes are well described in cell populations of the Leer más…
During the periparturient period of dairy cows, adipose tissues (AT) lipolysis fulfills, in part, energy deficits driven by parturition and lactogenesis. Lipolysis induces a remodeling process within AT that is characterized by inflammation with infiltration Leer más…
During the periparturient period of dairy cows, adipose tissues (AT) lipolysis fulfills, in part, energy deficits driven by fetal growth and the onset of lactation. Lipolysis induces a remodeling process within AT that is characterized Leer más…
